2. Signaling Pathways
  3. GPCR/G Protein
  4. Angiotensin Receptor
  5. AT1 Receptor Isoform
  6. AT1 Receptor Ligand

AT1 Receptor Ligand

AT1 Receptor Ligand (1):

Cat. No. Product Name Effect Purity
  • HY-125094
    L-162782
    		Ligand
    L-162782 is a high affinity AT1 receptor ligand for rat and human wild-type AT1 with IC50 values of 28.5 and 24.6 nM, respectively. L-162782 acts as a partial agonist (EC50 ≈ 30 nM) and insurmountable antagonist (IC50 = 6.5 μM) on wild-type rat AT1 receptors in COS-7 cells. L-162782 reduces Angiotensin II (HY-13948)-induced phosphatidylinositol turnover. L-162782 can be used for hypertension research.